Designing clinical research / Warren S. Browner, Thomas B. Newman, Steven R. Cummings, Deborah G. Grady, Alison J. Huang, Alka M. Kanaya, Mark J. Pletcher.Material type: TextPublisher: Philadelphia : Wolters Kluwer Health, 2023Edition: Fifth editionDescription: volume (451 pages) : illustrations 26 cmContent type: text Media type: unmediated Carrier type: volumeISBN: 9781975174408Subject(s): Epidemiologic Methods | Research DesignAdditional physical formats: Online version: Designing clinical researchDDC classification: 610.73 LOC classification: RA651
Preceded by Designing clinical research / Stephen B. Hulley ... [et al.]. 4th ed. 2013.
Includes bibliographical references and index.
Getting Started : The Anatomy and Physiology of Clinical Research -- Conceiving the Research Question and Developing the Study Plan -- Choosing the Study Participants : Specification, Sampling, and Recruitment -- Planning the Measurements : Precision, Accuracy, and Validity -- Getting Ready to Estimate Sample Size : Hypotheses and Underlying Principles -- Estimating Sample Size : Applications and Examples -- Addressing Ethical Issues -- Designing Cross-Sectional and Cohort Studies -- Designing Case Control Studies -- Estimating Causal Effects Using Observational Studies -- Designing a Randomized Blinded Trial -- Alternate Interventional Study Designs -- Designing Studies of Medical Tests -- Qualitative Approaches in Clinical Research -- Community-Engaged Research -- Research Using Existing Data or Specimens -- Designing, Selecting, and Administering Self-Reported Measures -- Study Implementation and Quality Control -- Data Management -- Writing a Proposal for Funding Research.
"For over 30 years, this title sets the standard as a practical guide for physicians, nurses, pharmacists and other practitioners involved in all forms of clinical and public health research. It presents the epidemiologic concepts in a reader-friendly way and suggests common sense approaches to the challenging judgments involved in designing, funding and implementing a study. Translated in many languages over the years, it is a manual for clinical research in it various flavors: clinical trials, observational epidemiology, translated science, patient-oriented research. Epidemiologic- terms and principles, presented advanced conceptual material in a practical and reader friendly way and suggested common sense approaches to many judgments involved in designing a study"--